鱼类主要组织相容性Ⅱ类基因的研究进展  

Progress on major histocompatibility class Ⅱ genes in fish

作　　者：于辉[1] 李波[1] 李华[1] 郭照良[1] 

机构地区：[1]佛山科学技术学院生命科学院,广东南海528231

出　　处：《中国水产科学》2007年第2期336-342,共7页Journal of Fishery Sciences of China

基　　金：国家自然科学基金资助项目(3030024630671500)

摘　　要：简要概述了鱼类主要组织相容性复合体(MHC)的遗传图谱及起源,对鱼类的MHCⅡ类基因的结构、抗原分子组成、表达及功能、遗传多态与进化机制作了较为详细的阐述。建议鱼类主要组织相容性复合体Ⅱ类基因座、等位基因组、等位基因及单倍型的命名规则尚需进一步规范。The genetic map and origin of major histocompatibility complex（MHC） in fish were briefly summarized in this paper. The gene structure, molecular composition, expression and function, the genetic polymorphism and evolution mechanism were also recapitulatively described in MHC Ⅱ.Considering the nomenclature system of fish MHC, the naming conventions of class- Ⅱ loci, allele groups, alleles and haplotypes particularly need to study,and it has great significance in resistance disease breeding and the development of molecular systematics in studing class- Ⅱof fish MHC in the future.

关 键 词：鱼 主要组织相容性复合体Ⅱ类基因 进展 

分 类 号：S813[农业科学—畜牧学]