加替沙星和左氧氟沙星治疗下呼吸道感染的成本-效果分析  

Cost-effectiveness Analysis of gatifloxacin and Levofloxacin in Treating Lower Respiratory Tract Infections

作　　者：赵辉[1] 

机构地区：[1]天津医科大学,天津300070

出　　处：《天津药学》2007年第1期49-50,共2页Tianjin Pharmacy

摘　　要：目的:评价加替沙星和左氧氟沙星治疗下呼吸道感染四种方案的经济效果。方法:将184例下呼吸道感染患者随机分为加替沙星序贯疗法组(a1)、静脉滴注组(a2)和左氧氟沙星序贯疗法组(b1)、静脉滴注组(b2),观察各组的临床治疗效果并进行成本-效果分析。结果:a1、a2、b1、b2组总有效率分别为88.4%、89.1%、87.5%和89.4%;细菌清除率分别为85.5%、89.1%、87.7%和89.3%;不良反应发生率分别为4.65%、6.52%、6.25%和6.38%。结论:通过成本-效果分析,左氧氟沙星序贯疗法是治疗下呼吸道感染的较佳方案。OBJECTIVE To evaluate the cost - effectiveness of gatifloxacin and levofloxacin in the treatment of lower respiratory tract infections. METHODS 184 cases of lower respiratory tract infections treated with gatifloxacin （group a1 ,a2 ） and levofloxacin （ group b1, b2 ） were evaluated by clinical effective ratethe analysis and evaluation were performed by cost - effectiveness analysis in pharmacoeconomics . RESULTS Total effective rates of group a1 ,a2 and b1 ,b2 were 88.4% ,89.1% and 87.5% ,89.4% respectivelytheir germ-clearance rate were 85.5% ,89.1% and 87.7% ,89.3% respeetivelytheir incidences, for adverse eft＇eeLs were 4.65% ,6.52% ,6.25% ,6.38%. CONCLUSION Levofloxacin sequential therapy is cheaper and has better cost - effectiveness advantage in the treatment of lower respiratory tract infections.

关 键 词：加替沙星 左氧氟沙星 序贯疗法 成本-效果分析 

分 类 号：F407.7[经济管理—产业经济]