B超监测下吉妮和TCu 380 A宫内节育器592例临床分析  

Clinical comparative study of 592 cases of GyneFix IN & TCu380A IUD indicated by B-ultrasonic

作　　者：刘小英[1] 周立晓[1] 尹华[1] 韩定英 张云珍[1] 曾颖[1] 黄永红[1] 严韶[1] 蔡梅[1] 魏素琼 吴洁[1] 何贝珍 吴秀云[1] 郑洁华[1] 欧苗苗 欧阳伟霞 江碧卿 崔建华（编校） 

机构地区：[1]广东省深圳市罗湖区计划生育服务中心,518019 [2]不详

出　　处：《中国妇幼保健》2007年第5期630-632,共3页Maternal and Child Health Care of China

基　　金：广东省深圳市科学技术局立项资助项目;合同编号为2003-K3:129

摘　　要：目的:①多中心观察B超监测下放置吉妮和TCu380A宫内节育器(IUD)并随访12月的临床效果;②探讨吉妮IUD近期脱落的原因。方法:随机分组并在B超监测下放置吉妮IUD289例,TCu380AIUD303例,术后1、3、6、12月定期妇科及B超随访,记录受试对象病史、术时和术后情况,用SPSS10.0软件包进行数据处理,以生命表方法统计结果并行显著性检验。结果:①术后疼痛症状发生情况TCu380AIUD组明显高于吉妮IUD组,差异有显著性(P<0.05);术后6、12月随访月经紊乱以TCu380AIUD组为高,差异有显著性(P<0.05)。②术后6月、12月生命表结果提示吉妮IUD组因出血和疼痛的终止率较TCu380AIUD组低,差异有显著性(P<0.05)。③子宫后位者易发生带器妊娠,脱落与月经量及置器医生放置IUD质量有关。结论:吉妮IUD的避孕效果与国际推荐使用的TCu380AIUD一致,置器后出血和疼痛副反应少于后者。引入B超监测IUD放置过程对杜绝放置的不安全隐患有重要作用,也是在监控和验证放置IUD质量、年轻医生的培训过程及基层推广应用中必须注意的问题。Objective： To evaluated clinical efficacy of GyneFix IN and TCu380A IUD indicated by B - ultrasonic after 12 months insertion and to explore the reasons of expulsion in late time after insertion. Methods： The study is a randomized multicentric comparative clinical trial. Health childbearing age women were allocated into GyneFix IN group （ n ffi 289）, TCu380A group （ n = 303）. The IUD was inserted indicated by B - ultrasonic. All the participants followed - up were arranged at 1, 3, 6, 12 months after insertion. The status of medical history, at insertion and after - insertion were recorded to analyze and compare with life table method. Results： （ 1 ） The number of women with complaint of pain was significantly lower in GyneFix IN group than that in TCu380A group after insertion （P 〈0.05）. The number of women with complaint of bleeding was less in GyneFix IN group at 6, 12 months after insertion （P 〈 0.05）. （2） The result of life - table method of pregnancy with IUD, expulsion and use IUD - related discontinuation was not statistically difference ; The discontinuation rate of bleeding and expulsion was less in GyneFix IN group （0. 35/100 women） than that in TCu380A group （2. 97/100 women, P 〈0.05）. （3） The pregnancy with IUD was high in retroversion flexion of uterus （ P 〈 0. 05） ; The expulsion was high in the cases of too much menses - amount and by insertion of the two doctors （P 〈 0. 05） . Conclusion： The contraceptive efficacy in GyneFix IN IUD is the same excellent as TCu380A IUD, and the side effect is lower than latter＇s. It is important to control and test ＆ verify the quality of inserted - IUD indicated by B - ultrasonic, to avoid hidden dangers of insecurity, especially in training doctors and extending appliance in the basic units of medicine ＆ family planning service.

关 键 词：吉妮宫内节育器 TCU 380 A宫内节育器 随机对照实验 B型超声波 

分 类 号：R169[医药卫生—公共卫生与预防医学]