乙型肝炎病毒传播母婴阻断1月龄婴儿乙型肝炎病毒标志物模式及临床意义  

Modes and significance of hepatitis B viral markers in 1-month-old infants by blocking mother-to-infant HBV transmission

作　　者：王建芳[1] 王建玲[1] 唐讯[1] 

机构地区：[1]东南大学医学院附属南京第二医院肝病研究室,江苏南京210003

出　　处：《世界感染杂志》2007年第1期59-60,共2页World Journal of Infection

摘　　要：目的探讨乙型肝炎病毒传播母婴阻断1月龄婴儿乙型肝炎病毒血清学标志物（HBVM）模式及临床意义，为乙型肝炎病毒母婴传播的阻断深入探讨提供依据。方法采用美国Abbott单克隆酶联免疫试剂检测孕妇及婴儿HBVM。结果经过分析归纳，临床上有14种HBVM模式。结论HBsAg、HBeAg、HBcAb三项阳性孕妇官内母婴阻断失败率仅为3．43％，因此，对婴儿加强疫苗接种或进行免疫干预有重要意义。Objective To investigate the modes and significance of hepatitis B viral markers （HBVM） in 1-month-old infants by blocking mother-to-infant HBV transmission and to provide basis to further study on blocking mother-to-infant HBV transmission. Methods Monoclonal enzyme-linked immunoadsorbent assay of Abbott Company （USA） was adopted to detect HBVM of pregnant women and infants. Results There were 14 type of HBVM modes after analysis and concluding. Conclusion In pregnant women of positive HBsAg, HBeAg and HBcAb, the rate of intra-uterus mother-to-infant blocking failure is 3.43%, so that it is very significant to strengthen vaccine inoculation or immune intervention in infants.

关 键 词：乙型肝炎病毒 母婴传播 阻断 

分 类 号：R373.21[医药卫生—病原生物学]