工作场所空气中过氧化苯甲酰高效液相色谱测定方法  

Determination of benzoyl peroxide in air of workplace by HPLC

作　　者：曲宁[1] 伊平[1] 聂莉[1] 杨琳[2] 

机构地区：[1]辽宁省疾病预防控制中心,沈阳110005 [2]东北大学,沈阳110005

出　　处：《中国卫生检验杂志》2007年第2期225-226,249,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的：建立工作场所空气中过氧化苯甲酰的高效液相色谱测定方法。方法：空气中过氧化苯甲酰用微孔滤膜采集，乙醚洗脱，经C18色谱柱分离，紫外检测器检测。结果：本法的检出限为1．0μg／ml，最低检出浓度0．22mg／m^3（采集45L样品）。在1．0—200μg／ml范围内，线性关系良好，r=0．9999。RSD在1．7％-5．2％之间。平均加标回收率为99．2％。用微孔滤膜采样，样品可保存2周。结论：方法操作简便、灵敏，可用于工作场所空气中过氧化苯甲酰的采集及测定。Objectiv： To establish a method for the determination of benzoyl peroxide in the air of workplace by HPLC. Methods- Benzoyl peroxide in the air of workplace was collected by cellulose ester membrane filter and extracted by ethyl ether,then the extracts were determined by HPLC with C18 column. Results：The detection limit was 1.0 μg/ml. The lowest detection concentration was 0. 22 mg/m^3. The linear equation was good between 1.0 -200 μg/ml, r = 0. 9999. The average recover was 99. 2% and sample was stable at two weeks. Conclusion ：The method is simple, sensitive and suitable for collection and detection of benzoyl peroxide in the air of workplace.

关 键 词：过氧化苯甲酰 高效液相色谱法 工作场所 

分 类 号：O657.7[理学—分析化学]