间歇式泡沫分离提取甘草中甘草酸的工艺研究  

Separation of glycyrrhizic acid by intermittence foam fractionation

作　　者：苏艳桃[1] 韩丽[1] 马鸿雁[1] 王虎山[1] 兰洁[1] 张艳艳[1] 杨明[1] 

机构地区：[1]成都中医药大学,四川成都611731

出　　处：《中草药》2007年第3期365-368,共4页Chinese Traditional and Herbal Drugs

摘　　要：目的优选间歇式泡沫分离甘草中甘草酸的最佳工艺条件。方法以回收率、富集比和产品质量分数为指标,单因素考察影响泡沫分离效果的各因素。结果间歇式泡沫分离甘草皂苷的最佳工艺条件为pH4、进料液中甘草酸质量浓度为0.23mg/mL、进气速度600mL/min、进料体积1000mL,此时泡沫相中甘草酸的回收率为91.9%,富集比为6.4,甘草酸质量分数32.3%。结论间歇式泡沫分离甘草中甘草酸是一种可行、有效的新型分离技术。Objective To optimize the enrichment process of glycyrrhizic acid by intermittence foam fractionation. Methods Investigating the every factors one by one, and the recovery obtained, enrichment radio and purity were used to optimize the process. Results This method was proved to be with a high recovery obtained which was 91.9%, enrichment radio was 6.4, and purity was 32.3%, while pH value was 4, concentration was 0.23 mg/mL, airflow rate was 600 mL/min, and volume was 1 000 mL. Conclusion Intermittence foam fractionation of glycyrrhizic acid is a new, viable, and effective method.

关 键 词：甘草 甘草酸 泡沫分离 

分 类 号：R282.2[医药卫生—中药学] R286.02[医药卫生—中医学]