影响α-TCP和HA生物陶瓷表面形成类骨磷灰石的形貌、结构的因素研究  

Critical factors on the morphology and structure of Bone-like apatite layers formed on α-TCP and HA surfaces

作　　者：田一平[1] 杨建华[1] 李晖[1] 郭灵虹[1] 

机构地区：[1]四川大学化学工程学院,成都610065

出　　处：《四川大学学报（自然科学版）》2007年第1期135-140,共6页Journal of Sichuan University(Natural Science Edition)

摘　　要：以磷酸三钙（α-TCP）和羟基磷灰石（HA）生物陶瓷为研究对象，采用X射线衍射（XRD）、扫描电子显微镜（SEM）研究α-TCP和HA在模拟体液（SBF）及磷酸盐缓冲液（PBS）中浸泡后表面类骨磷灰石的生长和形成，考察初始溶液的离子成分和浓度及陶瓷溶解性能对形成类骨磷灰石的形貌、结构的影响．实验表明：在SBF及PBS中浸泡后，HA仪在SBF中有少量的类骨磷灰石颗粒生成；α-TCP在SBF中表面形成类骨磷灰石颗粒，而在PBS中形成片状的磷酸八钙（OCP），XRD和SEM结果分别从结构和形态学方面确认磷酸八钙在1～3周可向颗粒状类骨磷灰石转化．The main attention of the present study was concentrated on the effects of ion intensity and type of immersion fluid,dissolution of calcium phosphate ceramics （CAP） on the morphology and structure of bone-like apatite formed on CaP ceramics surface. Hydroxyapatite（HA） and tricalcium phosphate（ α-TCP）were immersed into simulated body fluid（SBF） and phosphate buffer solution（PBS） from 1 to 3 weeks. The structure characteristics and morphology of layers formed on the ceramic surfaces were characterized by TF-XRD and SEM, respectively. The plate-like crystal layers, octacalcium phosphate （OCP）, were formed on the surface of α-TCP in PBS; but high-imperfect apatite particles, bone-like apatite, were formed in SBF. But for HA, there were only a few small high-imperfect apatite particles formed on the surface in SBF, and almost nothing in PBS. XRD and SEM results confirmed that OCP was able to be transferred to high-imperfect apatite in the immersion process.

关 键 词：Α-磷酸三钙 羟基磷灰石 类骨磷灰石 磷酸八钙 非对称XRD 

分 类 号：O647.11[理学—物理化学]