复方丹参CO_2超临界萃取液抗大鼠血栓形成的实验研究  

Experimental Study on the Antithrombotic Effects of Liquid Extraction of Salvia Miltiorrhiza Compound by CO_2 Supercritical Technology

作　　者：张旭静[1] 王素春[1] 郭吉平[1] 王桂清[1] 

机构地区：[1]上海市脑血管病防治研究所,上海201318

出　　处：《中国现代应用药学》2007年第1期14-16,共3页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的探讨复方丹参萃取液对大鼠实验性血栓形成的影响。方法采用大鼠颈总动脉-颈外静脉血流旁路法,进行复方丹参萃取液抗血栓形成实验,并检测其相关指标。结果复方丹参萃取液有明显抑制血栓形成,并有降低血小板聚集性的作用。结论复方丹参萃取液具有抗血栓形成的作用。OBJECTIVE To study the effect of Liquid extraction of Salvia Miltiorrhiza Compound on experimental thrombus formation in rats. METHODS The common carotid artery--external jugular vein by accessory pathway model in rats was used. The effect of Liquid extraction of Salvia Miltiorrhiza Compound for its antithrombotic effect was observed. At the same time, the related index were assessed. RESULTS Liquid extraction of Salvia Miltiorrhiza Compound inhibited the formation of experimental thrombus significantly and reduced aggregation of platelet. CONCLUSION It is suggested that Liquid extraction of Salvia Mihiorrhiza Compound has antithrombosis effect.

关 键 词：复方丹参萃取液 血栓 血小板聚集 大鼠 

分 类 号：R285.5[医药卫生—中药学]