伤速康涂膜剂的质量标准研究  

Study on Quality Standards for Shangsukang Film

作　　者：邓体瑛[1] 谢玲[1] 左亚杰[2] 邓桂明[2] 欧阳荣[2] 

机构地区：[1]湖南中医学院,长沙410007 [2]湖南中医学院附属第一医院,长沙410007

出　　处：《中国现代应用药学》2007年第1期56-58,共3页Chinese Journal of Modern Applied Pharmacy

基　　金：湖南省卫生厅中医药科研基金资助项目

摘　　要：目的建立伤速康涂膜剂的质量标准。方法采用TLC法对处方中大黄、栀子进行定性鉴别,并采用反相高效液相色谱法对涂膜剂中的大黄素、绿原酸进行含量测定。结果大黄素的平均回收率为101.8%,RSD为1.96%,绿原酸的平均回收率为102.1%,RSD为2.0%。结论该方法简便易行,重现性好,可作为本品的质量控制标准。OBJECTIVE To establish a quality standard for SHANGSUKANG Film. METHODS Radix et Rhizoma Rhei, Fructus Gardeniae in this prescription were identified by TLC. The content of Emodin and Chlorogenic acid were determined by HPLC. RESULTS The average recovery of Emodin was 101.8% ,and the RSD was 1.96%. The average recovery of Chlorogenic acid was 102.1%, and the RSD was 2.0%. CONCLUSION The method is simple, feasible and reproducible and can be used for the quality control of SHANGSUKANG Film.

关 键 词：伤速康涂膜剂 薄层鉴别 大黄素 绿原酸 高效液相色谱法 

分 类 号：R926.23[医药卫生—药学]