正交实验优选海南广藿香超临界二氧化碳萃取条件研究  

Studies on Pogostemon cablin Benth. with SFE by Orthogonal Experiments

作　　者：靳德军[1] 李泽友[1] 任兆平[1] 张俊清[1] 刘明生[1] 

机构地区：[1]海南医学院,海南海口571101

出　　处：《时珍国医国药》2007年第2期315-316,共2页Lishizhen Medicine and Materia Medica Research

基　　金：海南省教育厅高等学校教学科研指导性项目(No.hj200571)

摘　　要：目的用正交实验优化超临界CO2流体萃取海南广藿香挥发油成分的工艺条件。方法以萃取压力、萃取温度和萃取时间为考察因素,用出油率和广藿香醇含量为衡量指标综合考察海南广藿香的提取工艺。结果优选出较佳工艺条件为:萃取压力7.2 MPa,萃取温度40℃,萃取时间1 h。结论优选出了超临界CO2流体萃取海南广藿香挥发油成分的较佳工艺条件,为工业化开发提供了理论依据。Objective To optimize the technical parameters of Pogostemon cabin Benth. through controlling the different factors of SFE by orthogonal experiments. Methods Using the recovery rate of patchouli oil and content of Patchoulic alcohol as indexes, the effects of extraction pressure, extraction temperature , extraction time were evaluated by orthogonal experiments. Results The optimum conditions for extraction of Pogostemon cablin Benth. were as follows ：7.2 MPa,40℃ ,60 minutes. Conclusion It can be used for the theoretical basis.

关 键 词：海南广藿香 正交实验 超临界流体萃取 

分 类 号：R284.2[医药卫生—中药学]