血必净对脓毒症患者胃肠道黏膜保护作用的临床观察  

Effects of Xuebijing on Protecting Gastrointestinal Mucosa in Patients with Sepsis

作　　者：潘永[1] 林旋[1] 徐杰[1] 邓梦华[1] 冯锦昉[1] 张兴胜[1] 张斌[1] 

机构地区：[1]广东省佛山市中医院ICU,528000

出　　处：《中国全科医学》2007年第4期312-313,共2页Chinese General Practice

摘　　要：目的观察血必净注射液对脓毒症患者胃肠道黏膜的保护作用。方法将23例脓毒症患者随机分为血必净治疗组和常规ICU治疗组,常规ICU治疗组患者按受ICU常规治疗,血必净治疗组患者接受ICU常规治疗+血必净注射液60ml静滴,2次/d。测量两组患者治疗前及治疗72h时胃张力计盐水胃黏膜pH值(pHi)。结果治疗前两组患者pHi间差异无显著性意义(P>0.05),治疗后两组患者pHi间差异有显著性意义(P<0.01)。结论血必净注射液具有保护脓毒症患者胃肠道黏膜的作用。Objective To evaluate the effects of xuebijing on protecting gastrointestinal mucosa in patients with sepsis. Methods 23 cases with sepsis were randomized into control group （n = 10, conventional treatment） and study group （n = 13, 60 ml of xuebijing was injected intravenously twice a day, based on the conventional treatment）. The gastric phi was measured before the treatment and at the 72 h after the treatment respectively in two groups. Results There was no significant difference in gastric pHi between two groups before treatment （ P 〉 0.05 ）. The pHi was significantly higher in study group than that of control group after the treatment （ P 〈 0. 01 ）. Conclusion The traditional Chinese medicine xuebijing is effective in protecting the gastrointestinal mucosa in patients with sepsis.

关 键 词：血必净 脓毒症 胃肠道黏膜 

分 类 号：R59[医药卫生—内科学]