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出 处:《针刺研究》1996年第2期57-61,共5页Acupuncture Research
基 金:国家攀登计划项目!"经络的研究";天津市教委重点发展学科资助;霍英东教育基金
摘 要:肌肉注射山莨菪碱(654-2)建立大鼠胃运动减低模型,在肯定针刺足三里能提高胃运动机能的基础上,用经典钙调素拮抗剂三氟拉嗪溶液注射于足三里穴区,在局部穴区钙调素失活状态下,观察针刺足三里对胃运动低下的影响。结果表明,钙调素失活后在行针5分钟期间针效丧失,留针期间前10分钟针效有部分丧失,但随留针时间延长针效逐渐恢复。提示:钙调素失活可影响针效,胞内钙离子与钙调素复合物的激活可能是经络功能活动针效产生的重要环节之一。A model of the reducible movement of stomach in a big mouse was set up by injecting solution of 654-2. At first, the state of stomach movement was proved to be improved by acupuncture. After that,the activity of CaM in Zusanli point wirs lost by injecting TFP and effect of acupuncture on the stomach movement was studied. The result showed that the effect of acupuncture was abolished during manipulating the needles for 5 minutes. But retaining the needle for 25 minutes,the effect of acupuncture was recovered gradually. It indicates that the activity of Ca-CaM compounds may be of the key factor of acupuncture effect and one of the important links of the functional activity of meridians and collaterals.
分 类 号:R245.31[医药卫生—针灸推拿学] R259.730.5[医药卫生—中医临床基础]
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