电刺激皮层SⅡ区和电针对猫丘脑中央中核灌流液中β-EP含量的影响  

Effects of Electrical Stimulation of SⅡ and Electroacupuncture on β-Endorphin Contents in the Perfusate from the Nucleus Centrum Medianum of the Thalamus in Cats

作　　者：董晓彤[1] 王双坤[1] 王友京[1] 

机构地区：[1]中国中医研究院针灸研究所,北京100700

出　　处：《针刺研究》1996年第4期25-27,共3页Acupuncture Research

摘　　要：用推挽灌流技术结合放射免疫分析法，观察到电刺激大脑皮层体感Ⅱ区（SⅡ区）可使猫丘脑中央中核内β-内啡肽（β-EP）的释放增加；而电针“环跳”和“阳陵泉”不改变猫丘脑中央中核内β-EP的释放说明β-EP可能参与电刺激大脑皮层SⅡ区对丘脑中央中核的调节机制，而不参与电计“环跳“和“阳陵泉”穴对丘脑中央中核的调节过程。In order to probe into whether β-endorphin is involved in descending modu1ation of the somatosensory area(SⅡ)of the cerebral cortex on the nucleus centrum medianum(CM)of the thalamus and this mechanism of acupuncture analgesia, it Was investigated that effects of electrical stimulation of SⅡ and electroacupuncture on β-endorphin content in the perfusate from the nucleus CM.Adult cats were randomly divided into three groups: control, electroacupuncture and electrical stimulation of SⅡ. Push-pull perfusion technique was used to collect the perfusate from the nucleus CM β-endorphin contents in the perfusate were determined with radioimmunoassay.The results indicated that β-endorphin content in the perfusate was increased significantly by electrical stimulation of SⅡ and not by electroacupuncture, suggesting that the β-endorphin release from the nucleus CM was elevated by the stimulation of SⅡ and was not influenced by electroacupuncture. It is indicated that β-endorphin is possibly involved in the descending regulatory effect of electrical stimulation of SⅡ on the nucleus CM, but is not involved in the regulatory effect of electroacupuncture on the nucleus CM

关 键 词：丘脑中央中核 电针 脑刺激 内啡肽 SⅡ区 

分 类 号：R245.97[医药卫生—针灸推拿学]