板蓝根颗粒质量标准的研究  

Study on quality standard for Banlangen granules

作　　者：闵志良 况瑛 冷文金 

机构地区：[1]江西南昌济生制药厂,南昌330115

出　　处：《药物分析杂志》2007年第2期289-291,共3页Chinese Journal of Pharmaceutical Analysis

摘　　要：目的:建立板蓝根颗粒质量标准。方法:采用薄层色谱法对处方中的板蓝根进行定性鉴别,用高效液相色谱法测定处方中板蓝根有效成分靛玉红的含量。结果:在薄层色谱中检出板蓝根中的靛玉红;靛玉红在0.3852～7.704μg·mL^(-1)范围内呈良好的线性关系(r=0.9999),平均回收率为99.2%,RSD=1.3%。结论:所建立的方法可准确地进行定性、定量检测,可用于该制剂的质量控制。Objective：To establish the quality standard of radix Banlangen granules. Methods：Adopting TLC to make a qualitative identification of Banlangen in the prescription. Using HPLC to determine indirubin＇s content of Banlangen composition in the prescription. Results：The indirubin of Banlangen could be detected by TLC;The indirubin showed good linear relationship （ r = 0. 9999） in the range of 0. 3852 - 7. 704 μg · mL^-1 and the average recovery was 99. 2% with RSD of 1.3%. Conclusion：The methods were set up to make the qualitative and quantitative detection accurately, and maybe used in quality control of the pharmaceutics.

关 键 词：板蓝根颗粒 高效液相色谱法 靛玉红 薄层色谱法 质量标准 

分 类 号：R917[医药卫生—药物分析学]