PA－MSHA菌苗联合S－180瘤苗对荷瘤小鼠脾细胞增殖及IL_2产生的影响  

EFFECT OF PA-MSHA VACCINE COMBINED WITH S-180 TUMOR VACCINE ON PROLIFERATION OF LYMPHOCYTES AND PRODUCTION OF IL_2 IN TUMOR-BEARING MICE

作　　者：李淑华 张明策 刘艳萍 李宏伟 张洪林 

出　　处：《锦州医学院学报》1996年第6期7-8,共2页Journal of Jinzhou Medical College

摘　　要：通过ＰＡ－ＭＳＨＡ菌苗联合Ｓ－１８０瘤苗对荷瘤小鼠体外试验发现，ＰＡ－ＭＳＨＡ菌苗联合Ｓ－１８０瘤苗比单独用Ｓ－１８０瘤苗或ＰＡ－ＭＳＨＡ菌苗对荷瘤小鼠有更强的刺激淋巴细胞增殖和提高ＩＬ２产生的作用，提示联合瘤苗能显著提高荷瘤宿主的免疫功能。Vitro experiments on the effect of injection of PA-MSHA vaccine combined with S -180 tumor vaccine in tumor-bearing mice showed that in such mice the combined use of these vaccines had a stronger effect on stimulating the proliferation of lymphocytes and on increasing the production of IL2 than the use of either of them. This result suggested that the use of combined vaccines could markedly enhance the immunologic function of tumor-bearing organism.

关 键 词：S-180瘤苗 淋巴细胞增殖 IL2 绿脓杆菌 菌株制剂 

分 类 号：R392.7[医药卫生—免疫学]