Synthesis, Structure and Antibacterial Activities of 4-BBTS Schiff Base and Its Complexes  

作　　者：LI Pei-Fan LIU Bin WANG Jin-Ling 

机构地区：[1]Pharmacy Department of Tianjin Medical College, Tianjin 300222, China [2]College of Chemistry and Life, Tianjin Normal University, Tianjin 300074, China

出　　处：《Chinese Journal of Structural Chemistry》2007年第2期224-228,共5页结构化学（英文）

基　　金：This work was supported by the Natural Science Foundation of Tianjin (No. 003601711)

摘　　要：4-Bromobenzaldehyde thiosemicarbazone Schiff base （4-BBTS） and its Cu（Ⅱ）, Zn（Ⅱ）, Co（Ⅱ） and Ni（Ⅱ） complexes were synthesized and characterized by elemental analysis, UV, IR, MS, ^1H NMR, and molar conductivity. Using disc diffusion method, the antibacterial activity tests were conducted. The results revealed that the ligand as well as all the complexes exhibits good antibacterial activities against E. Coli. and S. Aureus. Moreover, Cu（Ⅱ） complex shows the best antibacterial activity, which provides beneficial reference for studying the relationship between the structures and performances.4-Bromobenzaldehyde thiosemicarbazone Schiff base （4-BBTS） and its Cu（Ⅱ）, Zn（Ⅱ）, Co（Ⅱ） and Ni（Ⅱ） complexes were synthesized and characterized by elemental analysis, UV, IR, MS, ^1H NMR, and molar conductivity. Using disc diffusion method, the antibacterial activity tests were conducted. The results revealed that the ligand as well as all the complexes exhibits good antibacterial activities against E. Coli. and S. Aureus. Moreover, Cu（Ⅱ） complex shows the best antibacterial activity, which provides beneficial reference for studying the relationship between the structures and performances.

关 键 词：4-BBTS Schiff base SYNTHESIS STRUCTURE antibacterial activity 

分 类 号：O626.41[理学—有机化学]