单纯性肥胖者胃肌电活动特征  

Characteristics of gastric myoelectrical activity of obese people

作　　者：常丽丽[1] 王智凤[2] 姚树坤[1] 

机构地区：[1]河北医科大学第四医院消化内科,河北石家庄050011 [2]中国医学科学院中国协和医科大学北京协和医院消化内科,北京100730

出　　处：《基础医学与临床》2007年第3期293-297,共5页Basic and Clinical Medicine

基　　金：河北省卫生厅2006年医学科学研究重点课题计划(06118)

摘　　要：目的探讨进餐前、后单纯性肥胖者的胃肌电活动特征。方法采用Digitrapper双电极EGG记录仪记录41例单纯性肥胖者餐前和餐后胃肌电活动,以32例正常体重健康志愿者为对照。结果①空腹状态下,肥胖组正常慢波节律百分比显著低于正常体重组(55.52±15.7比较70.83±14.31)(P<0.05);胃动过缓百分比显著高于正常体重组(17.07±10.88比较11.46±8.86)(P<0.05);无节律百分比显著高于正常体重组(9.70±5.70比较5.75±4.14)(P<0.01)。②进餐后,单纯性肥胖者正常慢波节律百分比仍显著低于正常体重组(53.19±17.77比较64.34±22.63)(P<0.05);主功率和胃动过速百分比显著高于正常体重组(36.50±4.86比较32.24±6.25,19.93±11.62比较12.94±11.72)(P<0.01和P<0.05)。③肥胖组餐后功率及振幅增加值显著高于正常体重组(P<0.01);餐后、餐前功率比显著高于正常体重组(P<0.05)。结论单纯性肥胖者空腹及餐后存在胃电节律异常,且餐后胃电主功率异常升高,可能是肥胖者胃动力亢进发生的电生理基础。Objective To explore the characteristics of gastric myoelectrical activity induced by meal in obese people. Methods Fourty-one cases of obese subjects were investigated with Digitrapper electrogastrography （EGG） before and after test meal, 32 healthy volunteers with normal body mass index were matched as control. Results （1）Before the meal, the percentage of normal slow waves （ N% ） in obese group was lower than that in control subjects（55.52 ± 15.7 vs 70. 83 ± 14. 31, P 〈0. 05） ; the percentage of bradygastria （ B% ） and the percentage of arhythmia （ AR% ） in obese group were higher than those in control group respectively （ 17.07 ± 10. 88 vs 11.46 ± 8. 86, 9. 70 ±5.7 vs 5.75 ±4. 14 ,P 〈0. 05 and P 〈0. 01 ）. （2）After meal, N% in the obese was lower than that of the control group （53.19 ± 17. 77 vs 64. 34 ± 22. 63, P 〈 0. 05 ） ; DP and the percentage of tachygastria（ T% ） in the obese were higher than those in control group respectively （36. 50 ± 4.86 vs 32. 24 ± 6. 25, 19. 93 ± 11.62 vs 12. 94 ± 11.72 , P 〈0. 01 and P 〈0. 05） . （3）The increase of DP , amplitude and power ratio （PR） in the obese were significantly higher than those in control group （ P 〈 0. 01 and P 〈 0. 05 ）. Conclusion At fasting state and post-meal state, obese people have abnormalities in gastric myoelectrical activity. Abnormal gastric electrical activity and DP＇ increase after meal may be the electrophysiological basis of gastric hypermotility in obese people.

关 键 词：单纯性肥胖 胃肌电活动 胃电图 

分 类 号：R589.2[医药卫生—内分泌]