高脂血症和游离脂肪酸与脂肪肝的相关性调查  

Correlation investigation of hyperlipidemia and free fatty acid with fatty liver

作　　者：曹友德[1] 李桂生[1] 李朝晖[1] 

机构地区：[1]湖南师范大学第一附属医院(湖南省人民医院),湖南长沙410005

出　　处：《中国现代医学杂志》2007年第4期461-463,共3页China Journal of Modern Medicine

摘　　要：目的探讨高脂血症及游离脂肪酸与脂肪肝发生的关系。方法测定2386名健康体检者的血脂、游离脂肪酸(FFA)水平,并做腹部B超。结果2386名体检者检出脂肪肝351例,男性脂肪肝患病率明显高于女性(P<0.01);脂肪肝组三酰甘油(TG)、总胆固醇(TC)和FFA明显高于非脂肪肝组(P<0.01);混合型高脂血症(高TG和高TC)组和高TG血症组脂肪肝的患病率及FFA水平明显高于血脂正常组(P<0.01),混合型高脂血症组脂肪肝发生率及FFA水平高于高TG血症组(P<0.05)。结论脂肪肝发病率与高脂血症尤其是高TG血症和游离脂肪酸密切相关。[Objective] To explore the relationship of hyperfipidemia and free fatty acid （FFA） with fatty fiver. [Methods] Detecting the level of blood lipid and FFA, and performed ultrasonic examination of the fiver with 2 386 cases of physical examination. [Result] 351 cases fatty fiver were found in 2 386 cases of physical examination, the positive rate of fatty fiver in male is higher than in female （P 〈0.01）; the level of triglyeeride （TG）, total cholesterol （TC） and FFA in fatty livers is higher than those in non-fatty livers （P 〈0.01）; mixed hyperlipidemia and hypetriglyeeridemia group had higher prevalence rate of fatty liver and level of FFA than normal lipid group （P 〈0.01）, mixed hyperlipidemia group had higher prevalence rate of fatty liver and level of FFA than hypetriglyeeridemia group （P 〈0.05）, [Conclusion] The prevalence rate of fatty fiver was closely correlated with hyperfipidemia especially hypetriglyceridemia and free fatty acid.

关 键 词：高脂血症 游离脂肪酸 脂肪肝 

分 类 号：R589.2[医药卫生—内分泌]