早期干预对新生儿缺氧缺血性脑病患儿预后影响的临床观察  

Clinical effect of earlier period intervention for the neonatal hypoxic - ischemic encephalopathy prognosis

作　　者：余巍[1] 钱蔚珍[1] 

机构地区：[1]广东药学院附属第一医院儿科,广东广州510080

出　　处：《现代保健（医学创新研究）》2007年第2期1-2,共2页

摘　　要：目的探讨早期干预对新生儿缺氧缺血性脑病患儿预后影响。方法将67例HIE患儿随机分为干预组35例，对照组32例；仅干预组从新生儿期开始接受为期24个月的干预治疗。两组患儿接受相同的综合治疗和育儿知识，所有的病例均于3．6、12、24月龄进行体格发育和智能发育检测。结果相同月龄时干预组的智力发育指数和运动发育指数均高于对照组（P〈0．05），干预组中脑瘫、智力低下、后遗症发生率明显低于对照组（P〈0．05）。但两组在体格发育方面比较差异无显著性（P〉0．05）。结论对新生儿缺氧缺血性脑病患儿给予早期持续的干预可改善其智力及运动发育，有效的降低后遗症的发生率。Objective To explore the Clinical effect of earlier period intervention on improving the prognosis of neonatal hypoxic - ischemic encephalopathy （HIE）. Methods Cases with HIE were divided into intervention group （35） and control group （32） randomly. Earlier period intervention Was only applied in the intervention group for 24 months from neonatal period . All cases accepted the same routine remedy and education. The physical examination and intelligence test were estimated in the infants of 3,6,12,24 months old. Results The intellectual developed quotient of intervention group was higher than that of the control group, at the same month age （ P 〈 0.05 ）, The incidence of cerebral palsy, intelligence disability and epilepsy in the intervention group was significantly lower than that in the control group （P 〈 0.05 ）, But there was no significantly difference of physical development in the two groups （P 〉 0.05）. Conclusion Giving earlier continuing intervention to the infants with HIE can improve their intelligential and physical development, reduce the incidence of sequela effectively .

关 键 词：新生儿 缺氧缺血性脑病 预后 早期干预 

分 类 号：R722.12[医药卫生—儿科]