板蓝根滴眼液治疗急性细菌性结膜炎临床疗效研究  

Clincal Research of Isatis Root Eyedrops on the Acute Bacterial Conjunctivitis

作　　者：戚朝秀[1] 吴笑梅[1] 王晓黎[1] 

机构地区：[1]中山大学附属第三医院眼科,广东广州510630

出　　处：《中药材》2007年第1期120-122,共3页Journal of Chinese Medicinal Materials

摘　　要：目的:观察中药制剂板蓝根滴眼液对急性细菌性结膜炎的临床疗效及安全性。方法:采用随机、双盲、平行对照的方法,将200例245只眼急性细菌性结膜炎患者随机分为板蓝根治疗组和左旋氧氟沙星对照组,每组各100例。实验组应用板蓝根滴眼液,对照组应用海伦(0.3%盐酸左旋氧氟沙星)滴眼液,每次一滴,每2 h一次,每日滴眼六次,总疗程为7天,观察两组用药后的临床疗效及其安全性指标。结果:实验组和对照组的临床疗效总有效率分别为90.0%和93%,差异无统计学意义(P>0.05),实验组和对照组分别有两例不良反应。结论:板蓝根滴眼液与海伦滴眼液相比,其治疗急性细菌性结膜炎的临床疗效确切,不良反应少。Objective ： To evaluate the efficacy and safety of isatis root eyedrops on the acute bacterial conjunctivitis. Methods ： A randomized, double-blind and parallel study was conducted on 200 cases. Isatis root eyedrops and Hailun eyedrops （levofloxacin eyedrops）, six times each day, were administered in test and control groups respectively. All patients have been observed for 7 days. The clinical effectiveness and reaction to drug after administration were assessed as the observation indexes. Results： The efficacy rates in test and control group were 90% and 93%, repectively, the difference between the two groups had no statistic significance （ P 〉 0. 05 ）. There have been two cases with side effects among the test and control groups respectively. Conclusion ： Isatis root eyedrops have an excellent efficacy and safety on the acute bacterial conjunctivitis.

关 键 词：板蓝根滴眼液 急性细菌性结膜炎 

分 类 号：R287[医药卫生—中药学]