广州市288例狂犬病疫苗免疫效果影响因素分析  

A Survey on the Efficacy of Rabies Vaccines in Guangzhou City

作　　者：刘楚钿[1] 曾利君[1] 岑咏珍[1] 陈美芬[1] 刘芳兰[1] 

机构地区：[1]广东省疾病预防控制中心,广州510300

出　　处：《热带医学杂志》2007年第2期178-180,共3页Journal of Tropical Medicine

摘　　要：目的了解广州市狂犬病疫苗免疫效果的影响因素,为如何提高免疫效果提供依据。方法采用统一调查问卷,由经过培训的护士,在知情同意下进行一对一面对面询问调查;对完成全程疫苗接种者采集血样检测狂犬病IgG抗体。结果共调查288人,男性137人,女性151人,平均年龄(33.83±18.07)岁;抗体阳转率为68.75%;影响抗体产生的因素有年龄、既往是否有狂犬病疫苗注射史和本次注射疫苗种类。结论年龄越小、既往注射过狂犬病疫苗和注射国产疫苗更容易产生抗体。Objective To study the factors affecting the efficacy of rabies immunization. Method Face-toface interview was conducted by trained nurses, and information was collected with the consent from the intcrvicwcs. Blood sample was collected from the volunteers receiving a complete course of immunization. Result A total of 288 subjects （137 male, 151 female, mean age 33.83±18.07） were studied. Sero-conversion rate was 68.75%. The age, history of vaccination, and the types of vaccine used in immunization are the factors affecting antibody production. Conclusion Sero-conversion is easily achieved in subjects with a younger age and a history of previous vaccination with rabies vaccine, especially nationally produced vaccines.

关 键 词：狂犬病 免疫 影响因素 

分 类 号：R512.99[医药卫生—内科学]