不同海拔高度成年男性精子参数的比较  

Comparison of Sperm Parameters Between Male Adults at Different Altitudes

作　　者：余良宽[1] 桂俊豪[2] 冯静[1] 胡边[2] 黄国香[2] 王铮[2] 王瑞[2] 余伍忠[2] 仇东辉[2] 

机构地区：[1]兰州军区乌鲁木齐总医院全军计划生育优生优育技术指导中心,新疆乌鲁木齐830000 [2]兰州军区乌鲁木齐总医院临床医学研究所,新疆乌鲁木齐830000

出　　处：《中华男科学杂志》2007年第2期122-124,共3页National Journal of Andrology

基　　金：兰州军区科研计划课题(LXH-200403)

摘　　要：目的:了解不同海拔长期缺氧暴露对男性精子功能的影响。方法:以驻留海拔5340m1～3年的28例健康男性青年为高海拔组,以34例现驻平均海拔3800m2～5年的健康男性青年为中海拔组,对照组为31例常年生活在1300m海拔地区的成年男性。收集精液标本,采用计算机辅助精液分析系统(CASA)对精子参数进行分析。结果:高海拔组的精子密度、精子曲线运动速度(VCL)、直线运动速度(VSL)、平均路径速度(VAP)和直线性(LIN)分别为(51.12±14.61)×106/ml、(48.17±13.52)μm/s、(32.64±6.70)μm/s、(41.21±9.32)μm/s和(52.24±8.14)%,均明显低于对照组(P<0.01或P<0.05)。中海拔组的精子密度、精子活率、VSL、VCL、LIN、VAP和ALH等参数较对照组亦有不同程度的下降,但差异无显著性(P>0.05)。结论:随着海拔高度的增加,高原缺氧暴露对成年男性的精子参数的负面影响愈明显。Objective： To investigate the influence of long-term anoxic exposure on the sperm function of male adults at different altitudes. Methods： A total of 28 male adults that had stayed at the altitude of 5 340 m for 1-3 years were included as a high-altitude group （ HAG）, 34 at the mean altitude of 3 800 m for 2-5 years as a middle-altitude group（MAG） and 31 permanently at the altitude of 1 300 m as controls. Semen specimens were collected and the real-time semen analysis was performed by using computer-assisted semen analysis （CASA） system. Results： The sperm density, VCL, VSL, VAP and LIN in the HAG were（ 51.12 ± 14.61 ） × 10^6/ ml, （48.17 ± 13.52）μm/s, （ 32.64 ± 6.70 ） μm/s, （ 41.21 ± 9.32 ） μm/s and 52.24 ±8.14, respectively, significantly lower than those of the control（ P 〈 0.01 or P 〈 0.05 ）. Compared with the control group, there was a progressive decrease in sperm concentration, sperm motility rate, VSL, VCL, LIN, VAP and ALH in the MAG. Conclusion ： The higher the altitude, the more obvious was the negative effect of anoxic exposure on the sperm function of male adults. Natl J Androl,2007,13 （2） ：122-124

关 键 词：精子参数 高原 缺氧 计算机辅助精液分析 成年男性 

分 类 号：R188[医药卫生—流行病学]