短暂性脑缺血发作持续时间与临床特征的相关研究  

The correlative study between clinical characteristics and symptom duration of transient ischemic attack

作　　者：朱武生[1] 樊新颖[1] 张华军[1] 毛晓薇[1] 郭芮兵[1] 马敏敏[1] 徐格林[1] 刘新峰[1] 

机构地区：[1]南京大学医学院临床学院南京军区南京总医院神经内科,江苏南京210002

出　　处：《中国实用内科杂志》2007年第6期447-448,共2页Chinese Journal of Practical Internal Medicine

基　　金：江苏省"六大人才高峰"项目(苏人通[2005]6);南京军区南京总医院院内课题(2005022)

摘　　要：目的探讨短暂性脑缺血(TIA)发作持续时间与临床特征的关系。方法从南京卒中注册数据库中选取2002年7月至2006年6月期间住院并符合研究方案的TIA患者172例,按照发作时间分为短时程TIA(<1h)和长时程TIA(1～24h)两组,分析两组患者的临床特征、弥散磁共振(DWI)异常病灶发生率。结果心房颤动、DWI异常多见于长时程TIA(P<0.05),多次发作(发作次数≥2)多见于短时程TIA(P<0.01)。两组在颅内外大血管病变方面差异无显著性意义(P>0.05)。结论房颤、DWI异常与长时程TIA相关,多次发作与短时程TIA相关。对TIA患者应根据发作时间不同进行相应的病因检查。Objective To investigate the relationship between clinical characteristics and symptom duration of transient ischemic attacks （TIA）. Methods A retrospective review of the clinical records of TIA patients was extracted from the database of Nanjing Stroke Registry Program （NSRP）. One hundred and seventy-two consecutive TIA patients consistent with research scheme were enrolled. They were divided into short duration group （ 〈 1 hour） and long duration group （ 1 hour to 〈 24 hours）. The clinical characteristics of the 2 groups were assessed. Results Atrial fibrillation （AF） and diffusion-weighted imaging （DWI） abnormality were seen more frequently in long duration group than in short duration group （P 〈 0. 05 ）. Multiple TIA （ number of attack ≥2） was more frequent in short duration group than in long duration group （ P 〈 0. 01 ）. There was no significant difference in intracranial and extracranial large artery disease between the 2 groups （P 〉 0. 05）. Conclusion AF and DWI are associated with long duration TIA. Multiple TIA is associated with short duration TIA. The corresponding etiology examination should be performed in TIA patients according to different duration.

关 键 词：短暂性脑缺血发作 心房颤动 磁共振成像 

分 类 号：R5[医药卫生—内科学]