中药有效部位抗心肌缺血作用机制研究进展  

Advances in Studying on Chinese Medicine Active Part of Anti-myocardial Ischemia Pharmacology

作　　者：张涵[1] 吕圭源[2] 陈素红[3] 周桂芬[2] 

机构地区：[1]上海中医药大学,上海201203 [2]浙江中医药大学,杭州310053 [3]温州医学院,温州325035

出　　处：《江西中医学院学报》2007年第1期85-88,共4页Journal of Jiangxi College of Traditional Chinese Medicine

摘　　要：目的:总结中药有效部位抗心肌缺血作用机制研究进展。方法:通过查阅近几年来有关中药有效部位抗实验性心肌缺血药理作用研究文献资料,并进行分析、综述。结果:中药有效部位可通过改善血流动力学、血液流变学、调节血管活性物质、钙平衡、保护线粒体、抑制细胞凋亡、清除自由基、促进血管新生等多方面发挥抗心肌缺血作用。结论:中药有效部位可在不同层次、多个靶点发挥抗心肌缺血作用。objective：To summary the progress on the anti-myocardial ischemia mechanism of Chinese medicine active part. Method： The literature about anti-experimental myocardial ischemia pharmacological effects of the Chinese medicine active part have been reviewed and analyzed by looking up the relevant articles in recent years. Result ：Chinese medicine active part play the anti-myocardial ischemia effects by improving the hemodynamic, hemorrheology; modulating vasoactive substance and calcium balance; protecting chondrosome;inhibiting apoptosis; clearing free radicle;promoting blood vessel neogenesis etc. Conclusion： Chinese medicine active part play the anti-myocardial ischemia pharmacological effects in different levels and many targets.

关 键 词：中药 有效部位 心肌缺血 药理作用 

分 类 号：R259[医药卫生—中西医结合]