支架血管成形术治疗颈动脉狭窄的临床研究  

Stent-assisted angioplasty for carotid artery stenosis

作　　者：李水彬[1] 俞万香[1] 成钢卫[1] 黄秉钦[1] 侯飞雁[1] 邹丽玲[1] 

机构地区：[1]广东省梅州市人民医院神经内科,514031

出　　处：《中华神经医学杂志》2007年第3期311-313,共3页Chinese Journal of Neuromedicine

摘　　要：目的探讨支架辅助血管成形术（CAS）治疗颈动脉狭窄的临床意义及其安全性。方法回顾性分析已经行支架辅助血管成形术的32例患者的临床资料，重点对手术方法、并发症、疗效进行总结。结果所有患者均有不同程度的反复短暂性脑缺血发作或不同部位的脑梗死．均经DSA证实有颈内动脉狭窄。所有病人都顺利完成支架植入，术前的平均狭窄率（NASCET方法计算）为（78．5±8．6）％，治疗以后的平均狭窄率为（17．2±8.3）％，两者相比差异有显著性意义（P〈0．05）；有5例患者出现术后低血压、心动过缓，有2例出现术后高灌注综合征，无一例发生脑梗死。术后随访6-12月，无颈动脉支架植入后的再狭窄的发生，未见脑梗死及短暂性脑缺血发作。结论支架辅助血管成形术是治疗颈动脉狭窄有效、安全的方法。Objective To explore the significance and safety of stent-assisted angioplasty in the treatment of carotid artery stenosis. Methods The clinical data of 32 patients of carotid artery stenosis having undergone were analyzed retrospectively, especially in aspects of operative methods, complications and curative effect. Results All the patients suffered fi＇om the recurrences of transient ischemia attack （TIA） or cerebral infarction in different region. The digital subtraction angiography （DSA） confirmed the presence of internal carotid stenosis. The stems were implanted successfully in all the patients. According to the measurements by NASCET method, the mean pre-operative stenosis rate was （78.5±8.6）% and the post-operative mean was （17.2±8.3）% （P〈0.05 vs pre-operation）. After operation, the complications included hypotension and bradycardia in 5 patients, and hyperperfusion syndrome in 2 patients; no cerebral infarction occurred. During the follow-up ranging 6-12 months, no recurrences of TIA or infarction were seen in all the patients. Conclusion The stent-assisted angioplasty is safe and effective for the treatment of carotid artery stenosis.

关 键 词：颈动脉狭窄 支架植入 血管成形术 

分 类 号：R686[医药卫生—骨科学]