参麦注射液对MODS氧合功能影响的临床研究  

The Clinical Study on the Effect of Shenmai Injection on Oxygenate Function

作　　者：寇兰俊[1] 刘清泉[1] 江其敏[1] 梁腾霄[1] 朱雪琪[1] 杨保林[1] 

机构地区：[1]北京中医药大学东直门医院,北京100700

出　　处：《中国中医急症》2007年第2期170-171,176,共3页Journal of Emergency in Traditional Chinese Medicine

摘　　要：目的观察参麦注射液对多脏器功能障碍综合征患者氧合功能的影响。方法对符合纳入标准的患者在采用常规治疗的基础上加用参麦注射液100ml,每日静点1次,并与未加用参麦注射液者进行对照;比较两组氧分压、氧饱和度并计算氧合指数、观察血乳酸含量等指标的变化以及患者14d脱机率及死亡率。结果加用参麦注射液治疗者与未加用参麦注射液治疗者血气分析及氧合指数、心率、呼吸、血乳酸含量及患者14d脱机率及死亡率比较差异有显者性。结论早期应用具有益气养阴扶正功能的参麦注射液,对多脏器功能障碍患者具有明显改善氧合功能、降低血乳酸含量、改善组织缺氧状态、提高脱机率、降低死亡率的作用。Objective： To investigate the effects of Shenmai Injection（参麦注射液） on oxygenate function of patients with multiorgan dysfunction syndrome （MODS）. Methods： The patients were divided into 2 groups. 20 cases were treated with conventional therapy and Shenmai Injection, the others were treated with out Shenmai In- jection. Oxygen partial pressure, 02 saturation and serum2 - hydroxypropionic acid were measured. Oxygenation index, the rate of weaning from mechanical ventilation in 14 days and death rate in the patients were calculated. Results： Those treated with Shenmai Injection obviously improved oxygenate function, hypoxia and the rate of weaning from mechanical ventilation, meanwhile decreased the content of serum 2- hydroxypropionic acid and death rate. Conclusion： Shenmai Injection could improved oxygenate function, reduce the level of lactate in blood, improve the anoxic condition in the tissue, and reduce the rate of weaning from mechanical rentilation and the rate of death.

关 键 词：多脏器功能障碍综合征 氧合功能 参麦注射液 

分 类 号：R442.8[医药卫生—诊断学]