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作 者:王桂花[1] 成子强[1] 高立坤[1] 朱国[1] 刁秀国[1]
机构地区:[1]山东农业大学动物科技学院,山东泰安271018
出 处:《动物医学进展》2007年第3期62-64,共3页Progress In Veterinary Medicine
基 金:山东省教育厅资助项目(J04C07)
摘 要:细胞因子是一类小分子多肽,通过自分泌和旁分泌传递细胞应答。细胞因子间复杂的相互作用控制着为保护机体免受病原体侵害而发生的炎症反应和特异性免疫应答,它是启动和维持机体防御功能的调节器,最终决定传递性应答反应类型和作用机制,作为效应分子暂时的、局部的来控制反应的发生范围和持续时间。文章介绍了细胞因子在禽传染病防治中的应用。Cytokines are polypeptides, and mediate cellular responses through autocrine and paracrine. Both inflammatory responses and specific immune responses to invasive microbes, which were evolved to protect the host from pathogens, are controlled by a complex network of cytokines. As regulator of the initiation and maintenance of host defenses, cytokines ultimately determine the type of response generated and the effector mechanisms generated to mediate resistance. As effector molecules,cytokines are produced transiently and locally to control the amplitude and duration of the response. The paper introduced the application of cytokines in prevention of infectious disease in poultry from three aspects.
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