锌与动物免疫细胞凋亡关系的研究进展  

Advance in the Relation Between Zinc and the Apoptosis of Animal Immune Cells

作　　者：王全溪[1] 李国平[1] 姜海军[1] 

机构地区：[1]福建农林大学动物科学学院,福建福州350002

出　　处：《动物医学进展》2007年第3期74-77,共4页Progress In Veterinary Medicine

基　　金：福建农林大学青年基金(05B08)

摘　　要：锌是机体必需的微量元素,它对免疫功能有很大影响,其在维持免疫系统的正常发育和功能方面有重要作用。锌与免疫系统的多种功能有关,对免疫系统的发育、稳定、调节有重要作用。缺锌将导致免疫器官萎缩、免疫细胞减少和抗体水平下降。研究表明,低锌能诱导淋巴细胞凋亡,而高锌抑制淋巴细胞凋亡;当锌浓度超过一定水平时,可产生神经毒性而诱导细胞凋亡。锌对细胞凋亡调控的可能机制和途径的研究有待进一步的研究。Zinc is the necessary trace element of body. It is important to keep the immune system development and immune function, tranquilization, regulation. Lack of zinc will induce the immune organ atrophy,immune cell decrease and antibody lever decrease. Research showed that low level zinc induceds lymphocyte apoptosis, and high level zinc inhibits lymphocyte apoptosis. However superscaler zinc will induce lymphocyte apoptosis. The mechanism and approach of Zinc inducing lymphocyte apoptosis should be farther researched.

关 键 词：锌 免疫细胞 细胞凋亡 

分 类 号：S852.4[农业科学—基础兽医学] S852.2[农业科学—兽医学]