N-(5-巯基-1,3,4-噻二唑-2-基)-N'-芳酰基硫脲的合成与生物活性  

Synthesis and biological activity of N-(5-mercapto-1,3,4-thiodiazol-2-yl]-N'-aroyl thioureas

作　　者：张正文[1] 

机构地区：[1]华中师范大学化学学院,武汉430079

出　　处：《华中师范大学学报（自然科学版）》2007年第1期88-90,共3页Journal of Central China Normal University：Natural Sciences

基　　金：国家自然科学基金资助项目(20072009)

摘　　要：通过2-氨基-5-巯基-1,3,4-噻二唑与芳酰基异硫氰酸酯反应,合成了12种新的芳酰基硫脲,其结构用红外光谱、核磁共振氢谱和元素分析进行了表征,初步的生物活性测定试验表明:部分目标化合物具有良好的植物生长调节活性,其中2c、2d和2h的生长素活性更优.Twelve new aroyl thioureas have been synthesized by the reaction of 2-amino- 5-mercapto-1,3,4-thiodiazole with aroyl isothiocyanates, their structures were characterized by IR, 1HNMR and elemental analysis. The preliminary biological activity tests showed that some target compounds have a good activity as plant growth regulator, and 2c, 2d, 2h have more excellent auxin activity.

关 键 词：1 3 4-噻二唑 芳酰基硫脲 生长素 合成 生物活性 

分 类 号：O621.29[理学—有机化学]