伴有黄疸的华支睾吸虫病临床特点与治疗分析  

Clinical characteristics and treatment of clonorchiasis sinensis patients with jaundice

作　　者：连粤湘[1] 林路平[1] 吴婉芬[1] 

机构地区：[1]广州市第八人民医院传染病研究所,广州510060

出　　处：《中华急诊医学杂志》2007年第3期309-310,共2页Chinese Journal of Emergency Medicine

摘　　要：目的总结伴有黄疸的华支睾吸虫病的临床特点及治疗方法。方法回顾性分析34例伴黄疸的华支睾吸虫病患者的临床特点，分别采用吡喹酮低剂量和常规剂量驱虫，观察其疗效及不良反应。结果深度黄疸患者占61．76％（21／34），合并肝内胆管扩张、肝内胆管炎占82．35％（28／34），而胆囊壁光滑及囊内回声无异常者达85．29％（29／34）。吡喹酮常规剂量组均可顺利消退黄疽，而采用低剂量吡喹酮治疗组难于消退黄疸。结论伴有黄疸的华支睾吸虫病患者多数黄疸较深且难以消退，常合并肝内胆管炎、肝内胆管扩张，而胆囊多无异常；粪便及十二指肠引流液查找虫卵是确诊的主要方法。黄疸的消退有赖于吡喹酮的驱虫治疗，但不宜采用低剂量吡喹酮驱虫，否则可能致黄疸加深。Objective To study the clinical characteristics and treatment of clonochiasis sinensis patients with jaundice. Method The clinical manifestations, treatment and prognosis of clonorehiasis sinensis in the 34 patients with jaundice were analyzed. Results The incidence rate of patients with severe jaundice was 61.76% （21/34）, and the rate of intrahepatic cholangiectasis and cholangitis was 82.35% （28/34）. The effect of patients treated with low dose of praziquantel was dissatisfied, Conclusions There were intrahepatic cholangiectasis and cholangitis in patients with clonorehiasis and jaundice. The diagnosis of clonorehiasis sinensis was made by the identification of eggs in the patient＇s feces or drain of duodenum. It could be necessary for the patients with clonorehiasis sinensis to receive high dose of praziquuntel.

关 键 词：华支睾吸虫病 黄疸 毗喹酮 

分 类 号：R686[医药卫生—骨科学]