百合多糖的药效学研究  

Pharmacodynamics Research of Lilium brownii Polysaccharide

作　　者：胡敏敏[1] 蔡宝昌[1] 张志杰[1] 张慧芳[1] 

机构地区：[1]南京中医药大学,南京210029

出　　处：《中药新药与临床药理》2007年第2期107-109,共3页Traditional Chinese Drug Research and Clinical Pharmacology

基　　金：国家科技部"十五"攻关科技专项(2001BA701A55-36)

摘　　要：目的对百合多糖进行药效学研究。方法通过耐缺氧实验及小鼠血清中SOD、MDA含量测定,网状内皮系统的碳粒廓清速度及免疫器官重量测定,血清溶血素含量测定,迟发型超敏反应等实验对百合多糖的主要药理指标进行考察。结果百合多糖具有增强小鼠耐缺氧能力、抗氧化及免疫增强作用。结论百合多糖是百合的主要活性成分之一。Objective To research the pharmacodynamics of lilium brownii Polysaccharide. Methods Five tests, including hypoxia tolerance test, serum content determination of SOD and MDA in mice, carbon clearance and weight determination of immune organ, content determination of serum hemolysin, and delayed - type hypersensitivity test were carried out to evaluate the main pharmacological indexes of lilium brownii Polysaccharide. Results Lilium brownii Polysaccharide can increase the hypoxia tolerance, anti - oxidation action and immuno - enhancing activity in mice. Conclusion Lilium browni Polysaccharide is one of the main active constituents of lilium brownii.

关 键 词：百合多糖 药效学 耐缺氧 抗氧化 免疫功能 

分 类 号：R285.5[医药卫生—中药学]