养胃合剂粗多糖对小鼠免疫功能的影响  

Effects of Polysaccharide Extracted from Yangwei Mixture on Immunologic Functions in Mice

作　　者：刘梅[1] 孟辉[2] 庞杰[1] 梁艳菊[1] 

机构地区：[1]广州中医药大学,广州510006 [2]暨南大学医学院中医系,广州510632

出　　处：《中药新药与临床药理》2007年第2期110-111,共2页Traditional Chinese Drug Research and Clinical Pharmacology

基　　金：广东省中医药局资助项目(301009)

摘　　要：目的观察养胃合剂复方多糖提取物对小鼠免疫功能的影响。方法建立小鼠环磷酰胺(CTX)免疫抑制模型,观察养胃合剂多糖提取物对小鼠免疫功能的影响。结果养胃合剂多糖能提高CTX致免疫抑制小鼠腹腔巨噬细胞的吞噬百分率,可促进溶血素形成,促进淋巴细胞转化。结论养胃合剂多糖有免疫促进作用,可对抗环磷酰胺的免疫抑制作用。Objective To observe the effects of polysaccharide extracted from Yangwei Mixture on immunologic functions in mice. Method Immuno - suppressant mice model was established by intraperitoneal injection of CTX . The effects of the polysaccharide were observed through phagocytosis test of mice celiac macrophagocyte and serum hemolysin level test as well as lymphocyte transformation test. Result The polysaccharide can obviously increase the percentage of phagocytosis of mice celiac macrophagocyte, accelerate the formation of hemolysin and promote the lymphocyte transformation. Conclusion Polysaccharide extracted from Yangwei Mixture is a good immuno - stimulant, and can counteract the immuno - suppression induced by CTX.

关 键 词：养胃合剂 免疫 环磷酰胺 

分 类 号：R285.5[医药卫生—中药学]