八元瓜环与N-苄基六次甲基四胺盐酸盐包结配合物的二维核磁共振研究  

Study on inclusion complex of cucurbit[8]uril with N-benzylhexamethylene tetramine chloride by using 2D NMR techniques

作　　者：张建新 薛赛凤[2] 祝黔江[2] 陶朱[2] 

机构地区：[1]中科院贵州省天然产物重点化学实验室,贵州贵阳550002 [2]贵州大学应用化学研究所,贵州贵阳550025

出　　处：《贵州大学学报（自然科学版）》2007年第2期198-200,191,共4页Journal of Guizhou University:Natural Sciences

基　　金：科技部国际科技合作重点项目(2003DF000030);贵州省省长基金资助项目(05008);贵州省国际科技合作重点项目

摘　　要：利用1H NMR及二维核磁共振谱NOESY和ROESY,对八元瓜环(Q[8])与N-苄基六次甲基四胺盐酸盐(M)相互作用的模式进行考察,结果表明两者形成包结比为1∶2的主客体配合物,两个客体分子的苯环部分进入瓜环的腔内,而六次甲基四胺部分处于瓜环的两个端口。The interaction model of the inclusion complex of cucurbit[ 8 ] uril （ Q [ 8 ] ） with N-benzyl-hexamethylene tetramine chloride （M） were assigned by using 2D NMR techniques such as NOESY and ROESY. The results revealed that two benzyl moieties of two guest M were included in the cavity of the host Q [ 8 ] to form a 1 ： 2 host to guest inclusion complex, the hexamethylene tetraminethe moieties of the guests were contained at the portals of the host Q [ 8 ].

关 键 词：八元瓜环 N-苄基六次甲基四胺盐酸盐 相互作用 二维核磁共振技术 

分 类 号：O657.32[理学—分析化学]