吊石苣苔的化学成分研究  

Studies on Chemical Constituents of Lysionotus pauciflorus

作　　者：冯卫生[1] 李倩[1] 郑晓珂[2] 

机构地区：[1]河南中医学院药学院,郑州450008 [2]河南中医学院基础医学院,郑州450008

出　　处：《中国药学杂志》2007年第5期337-338,共2页Chinese Pharmaceutical Journal

基　　金：教育部科学技术研究重点资助项目(2003078)

摘　　要：目的研究吊石苣苔(Lysionotus pauciflorus)的化学成分。方法利用Diaion HP-20,Toyopearl HW-40,硅胶柱等柱色谱技术进行分离纯化。根据化合物的理化性质和光谱数据鉴定结构。结果分离并鉴定了5个化合物的结构:D-(+)-棉子糖(Ⅰ),阿魏酸(Ⅱ),β-谷甾醇(Ⅲ),3-甲氧基-4-羟基苯乙酮(Ⅳ),邻苯二甲酸二异丁酯(Ⅴ)。结论化合物Ⅰ-Ⅴ均为首次从该植物中分离得到。OBJECTIVE To study the chemical constituents of Lysionotus pauciflorus. METHODS The compounds were isolated by Diaion HP -20, Toyopearl HW -40, silica gel column chromatography. Structures of these eompounds were identified by physiochemical properties and spectral analysis. RESULTS Five compounds were isolated from the 70% acetone-extracts, and their structures were identified as D-（ ＋ ）-raffinose（ Ⅰ ） ,ferulic acid （ Ⅱ） , β-sitosterol（ Ⅲ ） ,apocynin（ Ⅳ ） , di-isobutyl phthalate（ Ⅴ ）. CONCLUSION All the compounds are isolated from this plant for the first time.

关 键 词：吊石苣苔 苦苣苔科 化学成分 

分 类 号：R284[医药卫生—中药学]