新生儿先天性心脏病监测与随访  

Surveillance and follow up of congenital heart diseases in infants

作　　者：杨江帆[1] 杨戎威 李炜[1] 李萍[1] 何缦 宗酉明[1] 刘惠娟[1] 

机构地区：[1]浙江省嘉兴市妇幼保健院,314000

出　　处：《中国新生儿科杂志》2007年第2期72-75,共4页Chinese Journal of Neonatology

基　　金：浙江省计生委科研项目(1995-107)

摘　　要：目的探讨新生儿先天性心脏病(先心病)的发病情况和预后。方法(1)以彩色多普勒超声心动图配合尸检为主要诊断依据,对1992至1998年我院出生的31493例新生儿进行先心病发病情况前瞻性调查。(2)对1992至1995年出生的先心病患儿,随访3年。结果(1)以彩色多普勒超声心动图配合尸检,结合随访的修正诊断,检得先心病318例,患病率10.10‰。其中非青紫型255例,占80.2%,青紫型63例,占19.8%。室间隔缺损患病率5.14‰居首位。(2)318例先心病中新生儿期死亡35例,病死率11.0%,1992—1995年出生的167例先心病随访3年,死亡38例(22.8%),1岁内占94.7%,0～28d占68.4%。结论新生儿先心病发病率高,新生儿期是先心病死亡高峰年龄。Objective To study the prevalence and prognosis of congenital heart disease （CHD） in infants. Methods 31 493 infants born in our hospital from year 1992 to 1998 were selected and studied for the prevalence of CHD which was diagnosed by color doppler flon mapping （CDFM）. The infants with CHD who were born from year 1992 to 1995 in our hospital were followed up for three years. Results 318 cases of CHD were detected by color Doppler FM or autopsy combined with corrected diagnosis from follow up visits. The prevalence of CHD was 10.10%. Among these cases, 255 were non-cyanotic CHD （80.2%）, 63 cases （ 19.8% ） were cyanotic CHD. Ventricular septal defect （VSD） was the leading diagnosis of CHD （5.14‰）. Among the 318 cases, 35 infants died in neonatal period which lea- ded the fatality rate of 11.0%. 167 infants with CHD who were born between 1992 and 1995 were fol- lowed up for 3 years. 38 children died （22.8%） , 94.7% of them died when they were younger than 1 year old. And among those infants, 68.4% died in neonatal period. Conclusions The incidence of CHD is high in infants, and most death due to CHD happens in neonatal period.

关 键 词：心脏病 监测 生理学 随访研究 

分 类 号：R722.1[医药卫生—儿科]