革兰氏阴性菌中蛋白质亚细胞定位预测  

Prediction of Subcellular Localization of Proteins for Gram-negative Bacteria

作　　者：李凤敏 李前忠[1] 

机构地区：[1]内蒙古大学理工学院物理系

出　　处：《内蒙古大学学报（自然科学版）》2007年第1期39-43,共5页Journal of Inner Mongolia University：Natural Science Edition

基　　金：国家自然科学基金资助项目(30560039)

摘　　要：根据革兰氏阴性菌蛋白不同亚细胞位置、其一级结构中氨基酸含量、氨基酸的关联性及亲疏水性的不同,利用最小离散增量的方法,分别以20个氨基酸组份、400个氨基酸二联体组份及氨基酸亲疏水性在蛋白质上的分布为参数构成离散源,对革兰氏阴性菌蛋白的5类亚细胞定位进行预测,分别用se lf-cons istency方法和Jack-kn ife方法预测,均取得了较高的预测成功率.Based on the different amino acid composition, dipeptide composition, hydrophobic and hydrophilic amino acid distribution in different subcellular location,the sources of diversity are constituted by 20 amino acids, 400 adjacent residue-pairs, and hydrophobic and hydrophilic amino acid distributions in different sequences. By using the method of the least increment of diversity ,the subcellular localizations of proteins for Gram-negative bacteria are predicted. The high rates of correct prediction are obtained by self-consistency test and Jack-knife test.

关 键 词：革兰氏阴性菌 亚细胞位置 离散增量 

分 类 号：Q61[生物学—生物物理学]