神昌注射液质量标准研究  

Study on Quality Standards for Shenchang Injection

作　　者：花汝凤[1] 柯雪红[1] 魏刚[1] 方永奇[1] 

机构地区：[1]广州中医药大学第一附属医院实验中心,广州市510405

出　　处：《中国药房》2007年第9期675-676,共2页China Pharmacy

基　　金：广东省科技厅攻关项目(2003C34403)

摘　　要：目的:建立神昌注射液的质量标准。方法:采用薄层色谱法对处方中的冰片、石菖蒲挥发油进行定性鉴别;用高效液相色谱法测定注射液中β-细辛醚的含量。结果:薄层色谱法专属性强;β-细辛醚进样量在0.6323～1.2646μg范围内呈良好线性关系,平均回收率为99.92%(RSD=0.91%)。结论:所建标准可用于神昌注射液的质量控制。OBJECTIVE： To study the quality standards for Shenchang injection. METHODS： TLC was applied to identify the properties of Borneol and volatile oil of Rhizoma Acori Tatarinowii in the formula. HPLC was adopted to determine the content of β-asarone in Shenchang injection. RESULTS： β-asarone showed good linear relationship in the range of 0. 632 3- 1. 264 6μg. The average recovery of ammonium β- asarone was 99. 92% （RSD = 0.91% ） . CONCLUSION： The standard can be used for the quality control of Shenchang injection.

关 键 词：神昌注射液 薄层色谱 高效液相色谱 冰片 石菖蒲挥发油 Β-细辛醚 

分 类 号：R927.1[医药卫生—药学]