血纤维蛋白原与冠状动脉病变的关系  

Correlation between plasma fibrinogen and coronary artery disease

作　　者：王贵荣[1] 李双[1] 李跃香[1] 张得良[1] 

机构地区：[1]天津市大港医院,天津300270

出　　处：《海南医学》2007年第4期10-11,共2页Hainan Medical Journal

摘　　要：目的探讨冠心病(CHD)患者血纤维蛋白原(FIB)水平与冠状动脉病变程度和范围的相关性。方法行冠状动脉造影术的患者152例,冠心病组86例(其中单支病变组41例,多支病变组45例),男44例,女42例;对照组66例,男34例,女32例。测定血纤维蛋白原、胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)及血糖(Glu)水平进行2组间比较。结果冠心病组TG、TC、LDL、HDL及Glu水平与对照组比较差异无统计学意义(P>0.05),但FIB水平明显高于对照组(P<0.05),FIB水平与冠状动脉狭窄程度呈正相关(r=0.57,P<0.05)。结论FIB水平与冠状动脉病变程度和范围呈正相关。Objective To evaluate the correlation between plasma fibrinogen level to the extent, severity of coronary artery disease. Methods In 152 patients undergoing coronary angiography, plasma fibrinogen and lipids level were measured with usual procedures. Results There was a positive association between plasma fibrinogen level and the extent and severity of coronary artery disease. There was no difference in plasma lipids and glucose between coronary artery disease group and controls. Conclusions Elevated plasma fibrinogen correlated well with the extent, severity of the coronary artery disease.

关 键 词：冠心病 纤维蛋白原 

分 类 号：R541.4[医药卫生—心血管疾病]