冠心病病人血清超敏C反应蛋白、尿酸和三酰甘油水平检测  

MEASUREMENT OF SERUM hsCRP,UA AND TG IN PATIENTS WITH CORONARY HEART DISEASE

作　　者：辛萍[1] 田润华[2] 郑春喜 王秀丽[2] 

机构地区：[1]青岛大学医学院附属医院检验科,山东青岛266003 [2]青岛大学医学院生物化学与分子生物学教研室 [3]青岛市商业职工医院检验科

出　　处：《青岛大学医学院学报》2007年第1期66-67,共2页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：目的探讨冠心病病人空腹血清超敏c反应蛋白（hsCRP）、尿酸（UA）和三酰甘油（TG）水平改变及其相关关系。方法抽取49例冠心病病人空腹肘静脉血5mL，分离血清后用全自动生化分析仪分别测定血清hsCRP、UA及TG水平，并随机选择30例正常体检者作为对照。结果冠心病病人血清hsCRP、UA和TG与对照组相比均显著升高，差异有显著性（t=2．294～2．926，P＜0．05）。49例冠心病病人中hsCRP、UA和TG水平超出正常参考范围的人数分别为21、15和18例，三者间差异无显著性（X^2=1．581，P＞0．05）。Person相关分析表明，冠心病病人3项指标间无明显相关性（r=-0．18～0．60，P＞0．05）。结论血清hsCRP、UA和TG升高分别县冠心病的独立危险因素，三者联合检测将有助于冠心病的诊断、治疗和预后判定。Objective To assess the levels of serum hsCRP, UA and TG in patients with coronary heart disease （CHD） and their correlativity. Methods Venous blood （5 mL） was collected from the CHD patients （n=49） and normal healthy adults （n=30） separately. Serum hsCRP, UA and TG were assessed by automatic biochemistry analyzer. Results The levels of hsCRP, UA and TG in the patients were significantly higher than those of the normal healthy adults （t= 2. 294-2. 926, P〈 0.05）. The positive rates of hsCRP, UA and TG in the patients were 43% （21/49）, 31% （15/49） and 37% （18/49） respectively, the differences among them were not significant （r= -0. 18-0. 60, P〉0. 05）. Conclusion Increase of the levels of serum hsCRP, UA and TG is an independent risk factor which separately influence on patients with coronary heart disease. Combined assessments of the above parameters are of clinical significance in the diagnosis and treatment of the patients.

关 键 词：冠状动脉疾病 C反应蛋白质 尿酸 甘油三酯类 

分 类 号：R541.4[医药卫生—心血管疾病]