福辛普利与螺内酯治疗急性心肌梗死并发左心功能不全临床观察  

CLINICAL OBSERVATION ON EFFECTS OF FOSINOPRIL SODIUM AND ANTISTERONE ON ACUTE MYOCARDIAL INFARCTION WITH LEFT CARDIAC INSUFFICIENCY

作　　者：马先福[1] 马承泰[1] 刘春晖[1] 

机构地区：[1]青岛大学医学院附属医院急诊内科,山东青岛266003

出　　处：《青岛大学医学院学报》2007年第1期68-69,共2页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：目的观察福辛普利与螺内酯对急性心肌梗死(AMI)并发左心功能不全病人心功能的影响。方法44例AMI并发左心功能不全病人,在常规治疗的基础上给予福辛普利与螺内酯治疗,治疗前和治疗后2周测定血清钾、镁离子浓度,并采用超声心动图检测左心室射血分数(LVEF)。结果AMI病人用药2周后,其LVEF显著增高(t=2.36,P<0.05),血清钾、镁离子浓度变化不大。结论福辛普利与螺内酯可改善AMI并发左心功能不全病人的心功能。Objective To observe the effect of Fosinopril Sodium and antisterone on acute myocardial infarction（AMI） with left cardiac insufficiency. Methods Forty-four patients with AMI and left cardiac insufficiency were given Fosinopril Sodium and antisterone in addition to routine therapy. The concentrations of serum potassium and magnesium were measured, and left ventricular ejection fraction （LVEF） detected by echocardiogram before and two weeks after the treatment. Results LVEF remarkably improved, while serum ion concentration did not change significantly. Conclusion Fosinopril Sodium and antisterone could improve the cardiac function in patients with AMI and left cardiac insufficiency.

关 键 词：心肌梗死 心室功能障碍 福辛普利 螺内酯 

分 类 号：R542.22[医药卫生—心血管疾病]