AMI及不稳定型心绞痛病人血Lp(a)及Fbg含量的测定与分析  

AN OBSERVATION ON THE LEVELS OF LIPOPROTEIN (a) AND PLASMA FIBRINOGEN IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION

作　　者：夏舜英[1] 秦光明[1] 李翠琴[2] 

机构地区：[1]浙江医科大学附属第二医院心血管病研究室,杭州310009 [2]浙江医科大学附属第二医院内科实验室,杭州310009

出　　处：《急诊医学》1996年第4期211-213,共3页

摘　　要：对急性心肌梗死（AMI）病人采用酶联免疫法（ELISA）测血清脂蛋白（a）[Lp（a）]含量，并用饱和盐水沉淀比浊法测血浆纤维蛋白原（Fbg）的含量。结果显示：AMI病人（n=20）的血清Lp（a）含量高于不稳定型心绞痛（UAP）组（n=26）及对照组（n=50），并与对照组之间差异显著（P＜0．01）；AMI组病人（n=17）血浆Fbg含量高于UAP组（n=24）及对照组（n=50），并与UAP组及对照组比较均差异显著（P＜0．01）。结果提示：血清Lp（a）及血浆Fbg含量的升高是对AMI病人的两个重要观察指标，冠心病人的血浆Fbg明显增高预示有发生AMI的可能。Serum lipoprotein (a) [Lp (a)] levels were examined by enzmelinked immunosorbent assay (ELISA) in 20 patients with acute myocardial infarction (AMI), 26 patients with unstable angina pectoris (UAP) and in 50 healthy individuals. The results showed that the mean value of Lp (a) in the AMI group was significantly higher than that in healthy control group (P<0. 01). Plasma fibrinogen levels (Fbg) were also examined in 17 patients with AMI. The results showed that the mean value of plasma Fbg in AMI group was significantly higher than that in UAP group (n=24) and in healthy control group (n=50) (P<0.01). It was implicated in this study that elevated serum Lp (a) and plasma Fbg levels were two important observant sings in patients with AMI and that AMI might occur when plasma Fbg level increased obviously in a patient with coronary heart disease.

关 键 词：急性心肌梗死 脂蛋白(a) 纤维蛋白原 

分 类 号：R542.220.2[医药卫生—心血管疾病] R541.402[医药卫生—内科学]