湖州市社区人群病毒性肝炎感染特征研究  

A Study on Infectious Characteristics of Viral Hepatitis in Community Population in Huzhou

作　　者：金玫华[1] 韩建康[1] 沈建勇[1] 姚文庭[1] 邹勇[1] 

机构地区：[1]湖州市疾病预防控制中心,浙江湖州313000

出　　处：《浙江预防医学》2007年第3期7-9,共3页Zhejiang Journal of Preventive Medicine

基　　金：湖州市科技计划项目(编号:2006YS15)

摘　　要：目的了解湖州市社区人群病毒性肝炎的感染特征。方法对社区人群采用多阶段分层整群随机抽样方法抽取研究对象,进行个案调查和血清学检测。结果湖州市社区人群HAV、HBV、HCV、HDV、HEV标化感染率分别为55.74%、65.22%、0.12%、0%和38.88%。甲型肝炎总感染率城镇高于山区和平原水乡,感染率与年龄呈正相关。乙型肝炎总感染率男性高于女性,小年龄组即达较高水平;HBsAg携带率为4.14%,年龄分布呈中间高两头低,10岁以下携带率为0%;人群乙肝病毒标志物存在15种不同组合模式。戊型肝炎流行率地区间差异非常显著,城镇和平原水乡明显高于山区;流行率随年龄增长而逐渐上升。各型肝炎病毒混合感染比例较高,双重感染占37.52%。结论湖州市社区人群五型病毒性肝炎感染型别主要为HBV、HAV、HEV三种,流行特征各不相同,HEV感染率较高,HAV、HBV的感染率属中等水平,HCV、HDV的流行水平较低。Objective To investigate the infectious characteristics of viral hepatitis in community population in Huzhou. Methods Subjects were collected from community population by stratified multi-stage cluster sampling method. The data gathered from case investigation and serological detection. Results The standardized infectious rates of HAV, HBV, HCV, HDV and HEV were 55.74%, 65.22%, 0.12%, 0% and 38.88% respectively in community population in Huzhou. The total infectious rate of HAV which was positively associated with age was higher in towns than in mountainous areas and plains. The total infectious rate of HBV, which was at high level in younger group, was higher for men as compared with women. The carrier rate of HBsAg was 4. 14%, and the age distribution of that presented a phenomenon as high in the middle and low in the two ends, with the rate was 0% under 10-year-old population. There were 15 different combination patterns of HBV marker in population. The prevalence of HEV, which was positively associated with increased age, was significantly different between areas and that the level was obviously higher in towns and plains than in mountainous areas. The proportion of mixed infection of different hepatitis viruses was high and the proportion of daal infection was 37.52 %. Conclusions HBV, HAV and HCV are the major types of all the five hepatitis viruses in community population in Huzhou city. Different type of hepatitis viruses has different prevalent characteristics. The infectious rate is relatively higher in HEV, moderate in HAV and HBV, and lower in HCV and HDV.

关 键 词：社区人群 病毒性肝炎 血清流行病学 流行率 

分 类 号：R512.6[医药卫生—内科学]