2,4,6–三甲基苯甲酸的合成  

Synthesis of 2, 4, 6-trimethylbenzoic acid

作　　者：徐广宇[1] 徐建兵[2] 廖丽萍[1] 周伊[1] 臧阳陵[2] 

机构地区：[1]湖南师范大学化学化工学院,湖南长沙410081 [2]湖南省化工研究院精细化工研究所,湖南长沙410007

出　　处：《化工进展》2007年第3期430-432,共3页Chemical Industry and Engineering Progress

基　　金：湖南省自然科学基金资助项目(No.06JJ50024)

摘　　要：考察了在以均三甲苯为原料、CO2和AlCl3为酰化剂经Friedel-Crafts酰基化反应、水解合成2,4,6-三甲基苯甲酸工艺过程中,物料配比、反应温度等反应条件对收率的影响,确定了适宜的反应条件和后处理条件。通过此合成工艺,产品的产率可达83.3%。In this paper 2, 4, 6-trimethylbenzoic acid was synthesized by carboxylation of mesitylene in carbon dioxide-AlCl3 system. To optimize reaction conditions, experimental variables including reaction temperature and molar ratio were studied. The results showed the yield was as high as 83.3% when the molar ratio of mesitylene and AlCl3 was 0.7 ： 1 at room temperature.

关 键 词：均三甲苯 2 4 6-三甲基苯甲酸 CO2 合成 

分 类 号：TQ245.12[化学工程—有机化工]