微波作用下高分子咪唑盐催化合成含氟芳香物  

A Polymer Imidazole Salt as Phase-transfer Catalyst in Synthesis of Fluorinated Aromatics via Microwave Irradiation

作　　者：梁政勇[1] 李斌栋[1] 徐珍[1] 吕春绪[1] 

机构地区：[1]南京理工大学化工学院,南京210094

出　　处：《应用化学》2007年第4期406-410,共5页Chinese Journal of Applied Chemistry

基　　金：江苏省科技发展项目(BE 2004045)

摘　　要：高分子咪唑盐1是一种新型高分子相转移催化剂,具有制备简单、稳定性好、催化活性高等特点。TG分析表明,其分解温度可达350℃左右。在微波作用下,采用此高分子咪唑盐相转移催化剂于中等极性的非质子溶剂中成功制备了系列含氟硝基苯类化合物,其收率为72.1%～94.4%,反应时间较常规加热最多可缩短60%以上,拓宽了卤素交换氟化反应溶剂的选择空间。选用中等极性溶剂,反应中还可突出地体现出微波对反应的“非热效应”。Polymer imidazole salt 1 is a new kind of polymer phase transfer catalyst, which has the advantages of convenience for preparation, good thermal stability, and high catalytic activity. Its decomposition temperature determined by TGA is about 350 ℃. Some fluorinitrobenzene derivatives were prepared via halex fluorina- tion catalyzed by polymer imidazole salt from corresponding chloronitrobenzene derivatives under the irradiation of microwave. The yield of products was in a range of 72. 1% - 94. 4% , and the reaction time can be shortened by more than 60% in comparison with conventional heating. More aprotic solvents can be used in halogen-exchange fluorination under the irradiation of microwave. In addition, ＂non-thermal effect＂ can be shown obviously when the reaction is carried out in medium polar aprotic solvents.

关 键 词：微波化学 高分子咪唑盐 卤素交换氟化 氟代硝基苯 非热效应 

分 类 号：O621.2[理学—有机化学]