海藻酸钠-壳聚糖-粉末活性炭生物微胶囊的传递性能研究  

Study on the Diffusivity of Sodium Alginate-Chitosan-Powder Active-carbon Bio-microcapsule

作　　者：李朝霞[1] 

机构地区：[1]盐城工学院化学与生物工程学院,江苏盐城224003

出　　处：《化学通报》2007年第3期228-232,共5页Chemistry

基　　金：江苏省教育厅产业发展基金(JHB05-47);盐城市科技发展基金(YK200326-8)资助项目

摘　　要：测定不同分子量的聚乙二醇(PEG)溶液透过海藻酸钠-壳聚糖-粉末活性炭(SA-CA-PAC)生物微胶囊的性能,确定了SA-CA-PAC膜的截留分子量在PEG4000以下。研究了葡萄糖、乳糖、氨基酸等小分子的物质在SA-CA-PAC微胶囊中的扩散性能,用数学模型计算出了这些物质在微胶囊的混合扩散系数Dm以及相应的微胶囊膜层中扩散系数D1,结果表明小分子量的物质具有较好的扩散性能,且Dl<<Dm,说明微胶囊中的传质阻力主要集中在微胶囊膜层中,扫描电镜结果显示SA-CA-PAC微胶囊具有良好的膜结构。The diffusivity of polyethylene glycol （PEG） with various molecular mass in sodium alginate-chitosanpowder active carbon （SA-CA-PAC） microcapsules was measured. It was shown that molecular weight cut-off of the microcapsules membrane was lower than PEG4000. Meanwhile, the diffusivity of small solutes including glucose, lactose, and amino acid in the SA-CA-PAC microcapsules were determined. The mixed diffusion coefficients Dm and diffusion coefficients in capsular membrane D1 were calculated by a diffusion model. The results showed that the mixed diffusion coefficients D1 〈 〈 Dm indicated that the main resistance in mass transfer was mainly on the capsular membrane. The SEM micregraphs had shown that the SA-CA-PAC microcapsule had favorable membrane structure.

关 键 词：海藻酸钠 壳聚糖 粉末活性炭 生物微胶囊 传递性能 

分 类 号：O647[理学—物理化学]