Tei指数与心功能分级及血NT-proBNP的相关性研究  

Study on correlation among Tei index,cardiac functional grading and NT-proBNP

作　　者：谢桥涛[1] 宋建平[1] 戴敏[1] 谷云飞[1] 杨俊华[1] 蒋文平[1] 

机构地区：[1]苏州大学附属第一医院心内科,江苏省苏州市215006

出　　处：《实用诊断与治疗杂志》2007年第4期256-258,共3页Journal of Practical Diagnosis and Therapy

摘　　要：目的:探讨Tei指数评估左心室功能的应用价值。方法:106倒充血性心力衰竭患者,按照其入院时NYHA心功能分级分为心功能Ⅰ级,Ⅱ级,Ⅲ级,Ⅳ级组。22倒心功能正常者作为对照组。行超声心动图检查测出Tei指数、二尖瓣血流频谱测E峰、A峰、E/A值、LVEF值并检测血NT-proBNP。结果:充血性心力衰竭各组Tei指数明显高于对照组,差异有统计学意义(P<0．05)。随心功能障碍程度的加重,Tei指数升高,并且和心功能分级以及血NT-proBNP水平呈正相关(r分别为0.47,0.58,P<0.05)。结论:Tei指数与心功能分级以及血NT-proBNP水平有一定的相关性,能综合反映心脏的收缩和舒张功能。Objective To explore the correlation among Tei index, cardiac functional grading and NT-proBNP, investigate the value of Tei index for evaluating left ventricular function. Methods According to the NYHA cardiac functional grading method, 106 patients with congestive heart failure were divided into four classes as follows, grade Ⅰ （24 cases）, grade Ⅱ（26 cases）, gradeⅢ （29 cases） and grade Ⅳ （27 cases）. Control group consisted of 22 normal subjects. Tei index, E/A and EF were measured with echocardiography. The concentration of serum NT-proBNP was determined within 24 hours after the echocardiography measurement. Results Tei indexes were increased in every congestive heart failure group compared with control group （P 〈 0. 05）. With the sequence from NYHA functional grade Ⅰ to grade Ⅳ, Tei index was gradually increased; Tel index was positively correlated with left ventricular functional grades and serum NT-proBNP level respectively（r=0. 47, 0.58, P〈0. 05）. Conclusion Tei index is valuable and easy to estimate left ventricular systolic and diastolic function.

关 键 词：充血性心力衰竭 超声心动图 TEL指数 脑利钠肽 心功能分级 

分 类 号：R541.6[医药卫生—心血管疾病]