脂质体分析方法新进展  

Progress of methods for analysis of liposomes

作　　者：杨美燕[1] 梅兴国[1] 

机构地区：[1]军事医学科学院毒物药物研究所,北京100850

出　　处：《国外医学（药学分册）》2007年第2期119-122,共4页Foreign Medical Sciences(Section of Pharmarcy)

摘　　要：脂质体给药系统可降低药物的毒性,增加药物在靶点的聚集并提高药物的疗效。近代物理学实验技术的发展,使脂质体的质量研究进入分子水平。本文主要就近年来脂质体的定性定量分析方法的最新进展作一综述。Liposomes can increase the drug concentration in the target, reduce the toxicity and improve the therapeutic efficacy of drugs. The study of quality control of liposomes achieves molecular level with the development of modem physical techniques. In this article, techniques and methods that can be used for qualitiative and quantitative analysis of liposomes are described.

关 键 词：脂质体 粒径 包封率 脂双层 磷脂 

分 类 号：R944[医药卫生—药剂学]