溴甲酚绿分光光度法测定麻黄碱含量的研究  

Spectrophotometric Determination of Ephedrine with Bromocresol Green

作　　者：吴英[1] 谢红伟[1] 

机构地区：[1]贵州大学理学院,贵阳550025

出　　处：《分析科学学报》2007年第2期246-248,共3页Journal of Analytical Science

摘　　要：建立了溴甲酚绿分光光度法测定麻黄碱的方法。该方法最大吸收波长为620nm，摩尔吸光系数为1．78×10^4L·mol^-1·cm^-1，盐酸麻黄碱含量在20～120μg／mL范围内遵守比耳定律。用该法测定麻黄饮片及麻杏止咳片中的麻黄碱，平均回收率分别为98．9％、101．2％（n=3），相对标准偏差（RSD）〈2．31％。方法简单、快速，适用于生药及产品的质量控制。A Spectrophotometric method for the determination of ephedrine in ephedra epuisetina and ephedra epuisetina almond cough-relieving tablet has been proposed using bromocresol green. The maximum absorption wavelength was at 620 nm and molar absorption coefficient was 1.78×10^4 L·mol^-1·cm^-1. The calibration curve was linear in the range of 20～120μg/mL for ephedrine hydrochloride with correlation coefficient being 0. 9928（n=6）. The average recovery of two kinds of samples were 98.9% and 101.2%, respectively with RSD〈2.3%. This method is simple, rapid and would be an appropriate method for quality control in the pharmaceutical industry.

关 键 词：溴甲酚绿 麻黄碱 分光光度法 

分 类 号：O657.3[理学—分析化学]