黄芪肠内营养对2型糖尿病合并缺血性卒中病人营养代谢的影响  

Effect of Astragalus-supplemented enteral nutrition on nutritional metabolism in type-2 diabetic patients with ischemic stroke

作　　者：王晓希[1] 李旻[2] 阎敏[3] 刘载道[1] 卢志军[1] 汤萍[1] 

机构地区：[1]中南大学湘雅医院营养科,湖南长沙410008 [2]中南大学湘雅医院神经内科,湖南长沙410008 [3]中南大学湘雅医院药剂科,湖南长沙410008

出　　处：《肠外与肠内营养》2007年第2期108-110,共3页Parenteral & Enteral Nutrition

摘　　要：目的:研究黄芪肠内营养对2型糖尿病合并缺血性卒中病人营养代谢的影响。方法:将64例病人随机分为治疗组和对照组,每组32例。治疗组为黄芪水煎液(相当于生药60g)加改良匀浆膳,对照组为改良匀浆膳,两组给予105kJ/(kg.d)的营养支持,等氮、等热量供给,共30d。两组肠内营养支持前后分别检测空腹血糖及餐后2h血糖、血清胰岛素、血脂、清蛋白、转铁蛋白、血红蛋白、氮平衡等营养代谢指标。结果:治疗组肠内营养支持后胰岛素抵抗改善,空腹及餐后血糖降低,与对照组比较差异有显著性意义(P<0.05,P<0.01)。治疗组经营养支持后,负氮平衡转为正氮平衡,血清清蛋白升高,与对照组比较差异有显著性意义(P<0.05)。结论:黄芪肠内营养支持可明显改善2型糖尿病合并缺血性卒中病人胰岛素抵抗、血糖及蛋白质营养代谢。Objective ： To study the effect of Astragalus-supplemented enteral nutrition on nutritional metabolism in type-2 diabetic patients with ischemic stroke. Methods ：64 cases of type-2 diabetic patients with ischemic stroke were randomly divided into treatment group and control group. The treatment group was treated with homogenized diet and Radix Astragalis（ equivalent to 60g crude drug）, and the control group was treated with homogenized diet. Two groups were treated with nutrition support of 105kJ/（ kg · d） for 30 days. The levels of fasting and postprandial blood glucose,insulin,blood lipids,serum proteins and nitrogen balance were measured during enteral nutrition support. Results： ①Compared with the control group, insulin resistance index（HOMA-IR） was significantly improved （P 〈 0.01 ） and fasting and postprandial blood glucose were decreased （P 〈 0.01, P 〈 O. 05） in the treatment group . ②Compared with the control group, the levels of serum albumin and nitrogen balance increased in the treatment group（P 〈 0.05 ）. Conclusion：Astragalus-supplemented enteral nutrition can improve insulin resistanee、blood glucose and protein metabolism of type-2 diabetic patients with isehemie stroke.

关 键 词：2型糖尿病 缺血性卒中 黄芪 匀浆膳 

分 类 号：R259[医药卫生—中西医结合]