QCT椎体骨密度测定诊断骨质疏松症  

Diagnosis of osteoporosis using vertebra bone mineral density measurement by quantitative computed tomography

作　　者：沈宁江[1] 李一波[1] 陈文清[2] 刘光洪[2] 

机构地区：[1]海南省人民医院骨病外科,海口570311 [2]海南省人民医院CT室,海口570311

出　　处：《颈腰痛杂志》2007年第2期93-95,共3页The Journal of Cervicodynia and Lumbodynia

摘　　要：目的探讨定量CT(QCT)椎体骨密度(BMD)测定在诊断骨质疏松症中的临床价值和诊断标准。方法对53例健康无症状中老年人和68例临床拟诊骨质疏松患者进行L1-L4椎体BMD测定。结果健康中老年人BMD随年龄增长而明显降低,有显著性差异。以BMD≤x-2.0SD为诊断骨质疏松症标准有68例,且各年龄段的BMD值均明显低于骨量截断值;如以BMD≤x-2.5SD为诊断标准则有60例。结论QCT诊断骨质疏松症敏感、准确、重复性强,易于推广应用。以BMD≤x-2.0SD为诊断标准,更符合临床实际病例,并能减少漏诊。Objective To evaluate the clinical value and to explore diagnostic standard of osteoporosis with vertebra bone mineral density（BMD）by measurement using quantitative computed tomography（QCT）. Methods The BMD in vertebra of lumbar spine（L1-L4）were measured by QCT in 53 healthy middle-old-aged persons and 68 osteoporosis patients. Results The BMD of healthy middle-old-ages persons declined obviously with aging （P〈0.01）. If the diagnostic standard of osteoporosis was BMD ≤x-2.0SD,there were 68 patients. Which,the BMD values of different aged group were lower than the bone quantity block values. If the diagnostic criterion was BMD ≤x- 2.5SD,there were 60 cases. Conclusion As a method for diagnosing osteoporosis,QCT is highly sensitive,precise,reproducible and is easily applied. According to the diagnostic criterion with BMD≤x-2.0SD,it is more appropriate for clinical case and it can decrease rate of missed diagnosis.

关 键 词：定量CT 骨质疏松 骨密度测定 

分 类 号：R611.65[医药卫生—外科学]